Free Shipping

Mesothelioma Mesotheliomas

MESOTHELIOMA, Causes, Signs and Symptoms, Diagnosis and Treatment.

today's topic is mesothelioma

mesothelioma is a type of cancer arising

from the mesothelium the mesothelium is

the thin layer of protective tissue that

covers the outer surface of many

internal organs such as the heart

abdomen and the lungs mesothelioma is an

aggressive form that progresses and

spreads quickly mesothelioma is divided

into many different types depending on

the part of the mesothelium affected

mesothelioma that occurs in the pleura

or in the lining of the lungs is called

pleural mesothelioma it is the most

common form mesothelioma that occurs in

the lining of the abdomen called

peritoneum is referred to as a

peritoneal mesothelioma it is the second

most common form mesothelioma that

occurs in the protective layer of the

heart is referred to as pericardial

mesothelioma this type is the rarest it

occurs more in males than in females in

2015 about 60,000 800 people had the

disease and 32,000 deaths were recorded

only about 9% of people diagnosed with

the condition live longer than five

years causes the most common cause of


is an exposure to asbestos asbestos

refers to a set of six types of silicate

mineral that are naturally occurring

asbestos is made up of fibers that are

soft and flexible yet resistant to heat

fire and several chemicals asbestos is

used in a wide variety of applications

such as insulation brakes shingles

flooring and many other products when

asbestos is broken down such as when

removing asbestos insulation or during

the mining process dust is created

the fibers can be airborne they can then

be inhaled or swallowed and can settle

permanently in the lungs or stomach

where they cause irritation that causes

mesothelioma after asbestos exposure it

can take 20 to 40 years before

mesothelioma can develop factors that

may increase the risk of mesothelioma

include personal history of asbestos

exposure such as is seen in people who -

bestest work with asbestos products

produce products from asbestos or work

in a building containing asbestos living

with an asbestos worker symptoms

symptoms vary depending on the type of

mesothelioma pleural mesothelioma

shortness of breath unintended weight


coughing often painful chest pain under

the ribcage fatigue in severe cases

pneumothorax lung collapse tumor under

the skin of the chest peritoneal

mesothelioma abdominal swelling pain in

the abdomen weight loss fever night

sweats poor appetite

constipation vomiting in cases where the

cancer has spread to other parts of the

body trouble swallowing swelling of the

neck and face pericardial mesothelioma

shortness of breath low blood pressure

chest pain extreme fatigue heart

palpitations diagnosis diagnosis is

suspected with imaging scans but biopsy

is used for confirmation the doctor will

review your medical history and carry

out a physical examination to check for

lumps or any unusual signs followed by

chest x-ray and lung function tests a CT

scan or MRI is also usually used to

check for abnormalities a biopsy can be

used to confirm the diagnosis the type

of biopsy depends on where the symptoms

are options include fine needle

aspiration thoracoscopy laparoscopy

thoracotomy laparotomy diagnosis will

check if cancer is present and how far

it has spread the stage of the cancer is

between stage 1 to stage 4 stage 1

mesothelioma the cancer is confined to

the mesothelium and has not spread in

stage 4 mesothelioma cancer has spread

around the chest and to different organs

treatment treatment options depend on

the location the stage age and patients

general health for most people a cure

isn't possible because the condition is

usually diagnosed at the late stage when

it is impossible to remove the cancer

with surgery the only remaining option

in many cases is trying to control

cancer to make you more comfortable

treatment options may include surgery

when the condition is diagnosed early

surgeons work to remove the tumor in

cases where it is impossible to remove

the tumor surgery may help to reduce

symptoms surgical options may include

surgery to decrease fluid buildup

surgery to remove the tissue around the

lungs or pleura t'me or the tissue

lining the abdominal cavity pair o to

neck t'me radiation therapy that uses

powerful energy beams such as x-rays to

kill the cancer cells chemotherapy that

involves using medication injected

intravenously or taken orally to kill

the cancer cells.

Malignant Mesothelioma

and I'm a thoracic surgeon at Mayo

Clinic along with the Department of

Surgery the division of thoracic surgery

the division of pulmonary medicine and

medical oncology and radiation oncology

and radiology we've put together an

individual patient education video for

patients who have been diagnosed with

malignant mesothelioma we'll be talking

about ways that the tumor is caused

different treatment options different

opportunities for enrollment into

clinical trials and ways that you can

get different types of surgery we hope

that you find this educational and we

look forward to seeing you malignant

mesothelioma what is malignant

mesothelioma it is a rare type of cancer

that can develop in the thin layer of

tissue that covers most of your internal

organs that layer of tissue is called

the mesothelium this can be involving

the lungs the abdomen the heart are the

testicles possible causes of

mesothelioma include asbestos and many

other risk factors such as a personal

history of asbestos exposure living with

someone who works with asbestos exposure

to other fibrous materials or a family

history of mesothelioma some of the

symptoms and complications of

mesothelioma include the way that it may

affect tissue that surrounds the lung if

this happens it can cause symptoms such

as chest pain under the rib cage pain

during coughing shortness of breath

unusual lumps of tissue underneath the

skin on your chest or unexplained weight

loss some of the tests and diagnoses

that are available to you if you have

signs and symptoms that might indicate

music the glioma can be ordered by your

physician who will conduct a physical

exam to check for any lumps or unusual

signs he may listen he or she may listen

to your lungs palpate your abdomen and

ultimately a biopsy may be performed

depending on what area of your body is

affected your doctor may

choose one of the following biopsy

options including a needle biopsy a

camera inside the chest which is called

thoracoscopy a camera inside the abdomen

which is called laparoscopy or making an

open abdominal incision which is called

a laparotomy identifying the cancer

stage is one of the most important first

steps for patients who are diagnosed

with mesothelioma typically for patients

who have what's called pleural

mesothelioma which means it's on the

lining of the lung or the inside of the

chest are diagnosed by placing a tiny

single port into the chest it's

important that only one tiny port is

created because in the future that may

seed a tract of tumor that can grow to

the outside of the chest so when

patients go for surgery later on having

it removed by having only one port site

used to diagnose this tumor

it is easily excited at the time of

definitive surgery through this single

port a biopsy might be performed where

either the lining of the chest wall is

stripped away or the lining of the lung

is pulled away any bleeding is typically

treated directly at that time both the

bops the instrument and the camera go

through the same small port other ways

to create a stage to find out how

extensive the mesothelioma is and help

guide therapy include but are not

limited to a cat scan of the chest and

abdomen a magnetic resonance image

positron emission tomography also known

as pet endoscopic ultrasound also called

eus endobronchial ultrasound also called

EB us diagnostic staging laparoscopy

pulmonary function testing and

diagnostic thoracoscopy identifying the

cancer stage

is the most important part of your

treatment from malignant mesothelioma if

you've been diagnosed you want to make

sure that your doctor tells you what

your stage is based on these tests that

have been performed if they are unable

to give you your stage of mesothelioma

then you should seek a second opinion

from a group that can give you your

stage before you make decisions about

treatment when you look at your chest as

if you're looking at yourself reversed

to the left of the screen is your right

lung to the right of the screen is your

left lung the lining on top of your lung

is called the visceral pleura there is

space between the visceral pleura and

the chest wall the lining on the inside

of the chest wall is called the parietal

pleura deep to that you'll see the ribs

and the muscle in between the ribs which

is typically combined to create your

chest wall it is important to make sure

that the mesothelioma has not spread

through the diaphragm into the abdomen

if it begins inside the chest it is also

important to make sure that it has not

spread from the pleural space into the

mediastinum where the trachea and the

heart exists it is also important to

make sure that it has not gone through

the pericardium into the heart

all of these spreaded areas or involved

areas indicate that more advanced

disease may be present and might make

surgery not as feasible as it would have

been if it was not spread identifying

the cancer stage is one of the most

important first steps you may be

diagnosed with anywhere from stage 1 to

stage 4 mesothelioma treatment options

can include but are not limited to key

therapy radiation therapy and surgery

surgery and other treatment that may be

involved can be as limited as placing a

drain inside the chest the tunnels

underneath the skin with a fibrous cuff

allowing fluid to intermittently be

drained as it is connected to a vacuum

bottle this is sometimes referred to as

a pleura catheter but it may have many

other names and many companies make a

catheter such as this the catheter that

is placed in between the lining of the

lung and the lining of the chest wall

has many perforated holes allowing the

fluid that can sometimes cause the lung

to collapse and give you breathlessness

to be evacuated from the chest and

restore your ability to breathe and

allow you to be in control of your

disease chronically draining the fluid

and allowing your lung to re-expand

extended pleura come--and decortication

involves creating a thoracotomy which is

a large incision on the side of the

involved chest and after the ribs are

spread an incision is made between the

lining to enter what is called the

pleural space once the pleural space is

exposed the lining on the lung is

stripped away the lining on the heart

sac called the pericardium is also

removed and the lining on the diaphragm

is also removed

sometimes if an extended pleura t'me and

decortication is performed these

surfaces are completely removed and are

reconstructed with the mesh sometimes a

gore-tex mesh sometimes a bio composite

mesh and sometimes a non-absorbable

woven mesh it depends on your surgeons

preference what type of mesh they may

place you often want to ask your surgeon

what type of mesh they use to recreate

these areas if it was used so that you

know for your records

if an extra plural pneumonectomy is

performed the same surgery that we

talked about in the previous slide is

performed plus the additional resection

of the entire involved lung is removed

the left lung is removed if the

mesothelioma is on the left and the

right lung might be removed if the

mesothelioma is on the right most people

can tolerate having an entire lung

removed on one side once the lung is

removed the diaphragm and the

pericardium are also taken away to

complete the removal of all visible

disease once the visible disease has

been removed the area is reconstructed

and the chest is closed a chronic fluid

filled cavity will now exist where the

lung used to be alternative care options

are available to you and some of these

include but are not limited to

acupuncture for breathlessness relaxed

breathing exercises muscle relaxation

and sitting near a fan many of our pain

specialists and relaxation specialists

at Mayo Clinic can help you coping with

some of the symptoms associated with

advanced mesothelioma some final

thoughts include that a diagnosis of

mesothelioma can be very difficult to

cope with learn about mesothelioma to

make decisions about your care contact a

palliative care team studies have shown

that patients who have a very advanced

cancer who get plugged in early with the

palliative care team sometimes live

longer than if they didn't in the

beginning of their disease surround

yourself with support seek out other

people with cancer or similar cancers to

help support you plan ahead

our mesothelioma pathway is on this

slide and it is not meant to overwhelm

you but it is meant to educate you

patients present

with an effusion may either have a known

diagnosis of mesothelioma at the time

that they come to Mayo Clinic or they

may have a minimally invasive biopsy

through the single port as we showed

earlier there are three different types

of mesothelioma that may be diagnosed at

the time of diagnostic laparoscopy

thoracoscopy or treatment that is

sarcoma toid mesothelioma biphasic

mesothelioma or epithelioid mesothelioma

depending on the histology or the type

of mesothelioma decisions will be made

about your care a multidisciplinary

tumor board which is MD T P will meet to

discuss your care and we will review to

see if you could be enrolled into

clinical trials such as freezing the

mesothelioma a measles vaccine a

protocol called the smart protocol

perhaps a surgery involving extra

pleural pneumonectomy abbreviated by EPP

or cleric t'me and decortication

abbreviated as p and d there is a

staging checklist that we will go

through to make sure that you've had all

of the appropriate staging modalities

when they apply to you and these may

include a pet cat scan an endo bronchial

ultrasound a bronchoscopy a staging

laparoscopy sometimes a media sign osku

P and a video system Dorcas copic biopsy

through a single port approach based on

all the information that's gathered you

will then be given a stage of

mesothelioma your meeting mesothelioma

may create what's called a pleural

effusion and that can be treated by just

simply placing a needle into the chest

and draining the fluid or placing the

chronic drainage catheter as we showed

you earlier or placing a powder inside

the chest there are only very few

situations where we believe the powder

may help you and we recommend that you

refuse to have the powder placed inside

your chest until you've had an

opportunity to discuss your candidacy

for many of the other trials as the

powder will rule out your ability to

have many of these treatment options

offered to you there are many different

stages of mesothelioma and we will go

through this in great detail with you

once you come in to the clinic to be

evaluated we hope that you enjoyed this

discussion we look forward to seeing you

we hope you enjoyed this segment on

mesothelioma we hope you enjoyed hearing

about how to stage mesothelioma the

causes of mesothelioma and some of the

different treatment options if you have

questions feel free to call our office

thank you for this opportunity to visit

with you

Mesothelioma and Malignant Pleural Issues


a thoracic surgeon at the Swedish Cancer

Institute and Medical Center in Seattle

Washington I would like to talk to you

today about tumors involving the pleura

and in specific malignant pleural

mesothelioma in this podcast we will

talk about what the pleura is and

possible treatment options for cancer

involving the pleura with respect to

anatomy of the pleura each lobe of the

lung is covered by a double layer sac

that we term pleura this covers the lung

it lines the chest wall diaphragm and

mediastinum we called a layer that

covers the lung the visceral pleura we

term the layer that covers the chest

wall the parietal pleura pleura also

lines the diaphragm as well as the

pericardium the SAC around the heart the

space between the two pleural layers is

termed the pleural space

there are approximately two to three

thousand new cases of primary cancers of

the pleura or malignant pleural

mesothelioma that are diagnosed each

year in the United States we know that

remote exposure to asbestos is a risk

factor for developing mesothelioma

tumors of the pleura can also be in our

most often secondary to metastases from

cancer involving distant parts of the

body such as colon prostate and ovary

while primary pleural malignancies and

this is defined as tumors that arise

from the pleura itself are fairly

uncommon therefore physicians tend to

have a difficult time making the initial

diagnosis of mesothelioma we continue to

learn more about malignant pleural

mesothelioma with respect to the

diagnosis management and possible

treatment options we now know that for a

subgroup of patient

multi-modality therapy or the combined

use of chemotherapy radiation and

surgery is associated with better

outcomes than the use of any single one

of those treatment options alone

therefore survival of our patients with

mesothelioma is beginning to improve up

to 80% of cases of mesothelioma are

associated with asbestos exposure the

remaining cases can be related to family

contact as well as non asbestos type

causes people most often are diagnosed

with mesothelioma and their 50s to 70s

and males are affected more often than

females it can be difficult to

differentiate a malignant pleural

mesothelioma from a different type of

cancer that we call metastatic adeno

carcinoma these are two completely

different types of cancer with vastly

different treatment options as I

mentioned before pleural tumors are more

frequently metastatic cancers than

mesothelioma and so we utilize many

different tests to accurately make that

distinction it is crucial that we have

enough tissue sample or a large enough

biopsy specimen to adequately

characterize not only the tumor as a

mesothelioma but also to distinguish

which subtype of mesothelioma we have in

specific epithelioid sarcoma toyed or

mixed epithelioid mesothelioma is the

more favorable subtype of mesothelioma

and carries a greater chance of survival

after surgical and multi modality

therapy sarcoma toward mesothelioma is

composed of spindle-shaped cells and

these tumors tend to have a less

favorable outcome part of the difficulty

in making a diagnosis of mesothelioma

are there subtle symptoms that our

patient exhibits dyspnea or difficulty

with breathing is the most common

symptom and that is usually due to the

presence of a pleural effusion

characterized in blue this accumulates

in the spaces between the visceral

pleura and the parietal pleura in

between the lung and the chest wall

chest pain can also be common other

symptoms include cough loss of appetite

weight loss night sweats and even

hemoptysis or spitting up blood on

physical exam there may be decreased

breath sounds on the affected side there

can also be a mass in the chest wall and

this could be painful there are a number

of Radiologic tests that we order while

trying to establish the diagnosis

the stage which tells us how advanced

the cancer may be in determine if

surgery is feasible and in the best

interest of the patient CT scans of the

chest are usually one of the first tests

that we order it is readily available

and it provides some very useful data

PET scans help determine if there's any

suggestion of disease in the other lung

in the abdomen or in other areas of the

body at times MRI can suggest invasion

into the chest wall mediastinum or

across the diaphragm into the abdomen

this usually indicates that surgery

would not be an option that would

benefit the patient all the information

we gather including CT MRI PET as well

as histology from the tissue biopsy is

used to gain a better idea of the

anatomy of one's mesothelioma and

whether surgery will be of potential

benefit for the patient the first

invasive test used in an attempt to make

a diagnosis of mesothelioma is typically

a thoracentesis or when fluid is removed

from the pleural space a thoracentesis

is the use of a small catheter to drain

pleural fluid that is sent for analysis

to a pathologist to see if cancer cells

are indeed present it is not uncommon

that the pleural fluid is analyzed and

does not indicate a diagnosis of

mesothelioma or even cancer at all even

if cancer is present in that space

oftentimes the next step is the use of a

CT scan to guide a pleural biopsy

this yields a diagnosis of mesothelioma

approximately thirty to fifty percent of

the time better but still not great with

respect to making a definitive diagnosis

of mesothelioma lastly an operation can

be performed usually through a single

small incision in the chest wall a video

scope is introduced into the pleural

space and multiple biopsies are taken of

the pleural surfaces

this is often a diagnostic intervention

that results in a definitive diagnosis

of malignant pleural mesothelioma at

this point the patient typically is

referred to a thoracic surgeon with

experience and treating patients with

mesothelioma as is true with any cancer

we treat we stage every patient with

mesothelioma in other words we determine

how advanced we believe the cancer to be

when we attempt to determine the best

treatment option possible we utilize all

the data available to us including the

CT PET CT MRI tissue biopsy and

eventually add a procedure in the

operating room called a cervical

mediastinum skippy this is a procedure

where a small incision is made at the

base of the neck and mediastinal lymph

nodes are biopsied we now know that if

the mediastinal nodes are negative for

cancer meaning no cancer is present that

these patients live longer than if the

nodes are involved with cancer if we

suspect the possibility of mesothelioma

existing in the abdomen we may perform a

laparoscopy to assess this involves

going to the operating room where a

small incision and cameras are used to

obtain tissue to prove to prove the

presence or not of mesothelioma in the

abdomen there are two operations that

thoracic surgeons may consider

performing for patients with

mesothelioma these are named pleure

ectomy in decortication or extra pleural

pneumonectomy cleric t'me and

decortication is a surgical procedure

that involves removing both the viscera

and parietal pleura this leaves the lung

in place this can be a potential option

for patients with very minimal or very

advanced disease an extra pleural

pneumonectomy is the complete removal of

the lung with its visceral pleura the

parietal pleura the diaphragm and the

SAC around the heart termed the

pericardium we then reconstruct both the

pericardium as well as the diaphragm

using prosthetic material we believe

extra pleural pneumonectomy to be the

better choice for people who are strong

are younger or who have more bulky

disease there is no gold standard

therapy for mesothelioma your treatment

plan depends on the anatomy of your

tumor and your overall status sometimes

chemotherapy is done before surgery our

thoracic group from Swedish has a recent

publication describing our treatment

philosophy and results and patients with

mesothelioma treated with chemotherapy

first followed by surgery and then

radiation patients with mesothelioma are

better managed in centers where there is

experience and treating this type of

cancer as well as with the complex

surgical procedures required for removal

of the entire tumor only by centralizing

the care for the small number of new

patients with mesothelioma seen every

year to a limited number of medical

centers can we continue to study learn

and improve outcomes for our patients

fighting this cancer in the past

mesothelioma was considered to be a

disease that could not be treated in

which only pain management should be

offered we have come a long way from

those days we now know there are

interventions that can help certain

patients live longer and more

comfortably the surgeries that we offer

to patients have improved our ability to

make accurate diagnosis

before we head to the operating room we

continue to experiment do research and

study our results critically thank you

for listening to the plugged into your

health cancer podcast program

mesothelioma and malignant pleural

issues in thoracic surgeries for more

information please contact your thoracic


Our clients

Eu comprei e gostei desse 2 Conjunto Cropped Renda Sensual Lingerie Moda Intima